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The U.S. Open 2023 tennis tournament is now at the semifinal stage, with the women’s matchups taking place on Friday.

The final four features two American talents, with six ranked Coco Gauff taking on the number ten ranked Karolina Muchova from the Czech Republic, and Madison Keys facing the number two ranked Aryna Sabalenka, who is now considered the favorite to win the competition.

Sabalenka has U.S. Open tennis betting odds of +100 to win the tournament, while Coco Gauff is just behind her at +175. Both have been extremely impressive in the competition so far, and could meet in the final for a thrilling clash.

That’s not to write off their opponents in the semifinal though, with all four women playing elite level tennis on their way to a potential final.

These are our U.S. Open best bets for the semifinal round, with a pick for each game as we head towards the final this weekend.

Coco Gauff vs Karolina Muchova Odds, Moneyline & Spread – US Open Betting Women’s Odds 9/8

Match Winner: Coco Gauff -223, Karolina Muchova +175
1st Set Winner: Coco Gauff -182, Karolina Muchova +130
2nd Set Winner: Coco Gauff -182, Karolina Muchova +130
Total Games:
(19.5) Over -200, Under +140
(20.5) Over -154, Under +110
(21.5) Over -125, Under -112
(22.5) Over +105, Under -143
(23.5) Over +120, Under -167

Coco Gauff vs Karolina Muchova Prediction and Pick

The U.S. Open semifinal between Coco Gauff and Karolina Muchova is a repeat matchup of the Cincinnati Masters final that took place on the 20th of August.

Gauff won that matchup in straight sets having taken out the world number one Iga Swiatek in the semi final, and is now looking to win back to back tournaments with a Grand Slam victory at the U.S. Open.

Coco presents a different challenge for Karolina Muchova, who has been thrashing her way through the competition so far. The likes of Taylor Townsend, Wang Xinyu and even Sorana Cirstea in the quarter final, while great tennis players, don’t possess the same level of power as Gauff does.

The American is in fine form as of late, winning both the Citi Open and the Cincinnati Masters in the last couple of months. She’s playing with a lot of confidence and will go into this semifinal against Muchova with the upper hand considering their most recent encounter.

While the Czech 27 year old will have learned from the experience in Cincinnati, Gauff feels like the superior player here, and I have her winning in three sets with the first of my U.S. Open best bets for the semifinals.

The Pick: Coco Gauff to win 2-1 (+280)

Madison Keys vs Aryna Sabalenka Odds, Moneyline & Spread – US Open Betting Women’s Odds 9/8

Match Winner: Madison Keys +200, Aryna Sabalenka -264
1st Set Winner: Madison Keys +160, Aryna Sabalenka -225
2nd Set Winner: Madison Keys +160, Aryna Sabalenka -225
Total Games:
(19.5) Over -200, Under +140
(20.5) Over -154, Under +110
(21.5) Over -118, Under -118
(22.5) Over +110, Under -154
(23.5) Over +130, Under -182
Madison Keys vs Aryna Sabalenka Prediction and Pick

Aryna Sabalenka was our original pick to win the competition, with US tennis Open betting odds at +450 before the tournament got started. She now finds herself in the final four of a Grand Slam competition once again, and at this point she’s the favorite to win the U.S. Open with an edge over Coco Gauff in the standings.

Sabalenka has been the epitome of consistency as of late, featuring in every single semifinal of every Grand Slam in the last year, including a devastating loss in the Wimbledon semifinal.

The Belarusian star now finds herself in control of her own destiny with an opportunity to claim her second Grand Slam title, having won the Australian Open earlier this year.

There aren’t many in better form than the 25-year-old right now, who is ranked second in the world only to Iga Swiatek. However, her opponent in the semifinal has the home court advantage and plenty of momentum of her own heading into Friday’s semifinal.

Madison Keys made the quarter finals at Wimbledon back in July having won the Eastbourne International in the previous tournament with a win over Daria Kasatkina in the final.

The U.S. national is yet to win a Grand Slam, with her only appearance in a final coming in the 2017 U.S. Open final against Sloane Stephens. She is now on her best run at the tournament since then, and while the underdog, will be throwing everything she has into causing the upset with the chance to finally win a major competition.

Madison Keys plays her best tennis on hard courts, so she should have plenty of confidence, but I’m not sure it's going to be enough to take down Sabalenka in her current form.

I have her winning in straight sets in my best bets for the U.S. Open semifinals, with odds at +100 feeling like good value for the incoming parlay below.

The Pick: Aryna Sabalenka to win 2-0 (+100)

Best US Open Tennis Parlays Bets Today for Semi Final games: 2-Leg Parlay Picks (+600)

With two matchups on the cards, check out these US Open tennis odds for a two-leg parlay covering both picks in today's article.

Coco Gauff Set Betting

Leg-1 Parlay Pick: Coco Gauff to win 2-1 (+280)

Aryna Sabalenka Set Betting

Leg-2 Parlay Pick: Aryna Sabalenka to win 2-0 (+100)

Odds are subject to change*

US OPEN TENNIS PARLAY PICKS @(+600): (Bet $100 to Win $700). Get the best odds at Betway Sportsbook.

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