Find NFL odds throughout the season on the Betway sportsbook. You'll find all the latest spreads, totals, money lines and Betway Promotions. Or call it how you see it with our live NFL betting in-play. Betting on NFL has never been easier. All your needs are covered at our online sportsbook.

Visit Betway’s NFL picks page for picks and predictions throughout the regular and playoffs season.

How to bet on NFL games

NFL Money Line

Money line is the simplest way to bet on an NFL game and is one of the most popular bets placed on the Betway sportsbook.

A money line bet is a wager on the team you think will win the game. Money line markets give you the option to bet on the two teams involved, simply select the team you want to back and enter your stake to place the bet. 

To place a money line bet, you need to be able to read money line odds, also known as American odds. Within a money line market, one team will be the favorite, and one will be the underdog, and this is reflected in the odds. For example, in a game between the New England Patriots and Buffalo Bills, the odds would look something like:

Patriots +135

Bills -155

In this scenario, the Bills are the favorites, which is denoted by the minus sign, while the Patriots are the underdogs, as indicated by the plus sign.

In the case of the Bills, a minus sign indicates the amount of money you must bet to win $100, so if you bet $155 on the Bills and they won, you would receive $100 in winnings.

Looking at the Patriots, a plus sign indicates the amount of money you would win if you bet $100, so if you bet $100 on New England and they won, you would receive $135 in winnings.

NFL Point Spreads

In NFL betting, the point spread is essentially a handicap that levels out the odds, allowing bettors to back both teams with a relatively even chance of success.

Point spread betting works through the application of a handicap to a game, which takes points away from the favorite and gives them to the underdog.

In the point spread market on our NFL betting page, you will see one team with a minus sign before the spread, and one with a plus sign. Just as we see in the money line market, the minus sign indicates the favorite, and the plus indicates the underdog.

Using the Patriots vs Bills example again, the point spread market could look something like this:

Patriots +4.5

Bills -4.5

This means that if you bet on the Patriots, 4.5 points will be added to their final score, and your bet will be a winner if they remain within five points of the Bills.

If you bet on the Bills, 4.5 points will be taken away, and your bet will only be a winner if they win by five points or more.

NFL Over/Under

Over/under markets in sports betting are also known as point totals, and are another very popular way of wagering on NFL games.

These markets allow you to bet on the total number of points that will be scored between both teams in an NFL game.

An over/under market will have a set points total, and give you the option to bet on the over or under.

For example, say the Patriots are playing the Bills and the over/under line is set at 34.5. You can either bet there will be 35 points or more scored in the game, or fewer than that.

Over/under markets don’t tend to offer much value, but they can usually be combined with other bets in a same-game parlay to lengthen the odds. For example, you could combine a money line bet and over/under bet into one wager for a bigger potential payout.

NFL Prop Bets

Another way of betting on NFL is through proposition bets, known as props. Prop bets allow you to bet on a specific outcome to happen in a match.

The most common form of prop bets are player props, which give you the chance to bet on a specific player achieving (or not) something within the game.

Using the Patriots vs Bills example again, the player prop section on the sportsbook may offer you to bet on Josh Allen passing for over/under 199.5 yards in the game. Or, you may want to bet on Stefon Diggs scoring a touchdown.

Player prop markets are highly varied, and offer you the chance to bet on a wide array of outcomes within a single game.

Props can also be combined with other markets in a same-game parlay, so you could bet on the Bills to win, Allen to throw for over 199.5 yards and Diggs to score a touchdown in a single bet.

NFL Parlays

Parlays are bets which are made up of multiple legs. To put it simply, if you combine two or more wagers into a single bet, that is a parlay.

Parlay bets are a good way of lengthening your odds and increasing your potential payout, but they are harder to win, because each part of the bet must come in for the parlay to be successful.

For example, you may have your eye on four teams you think will win their NFL games on a particular weekend – the Bills, Chiefs, Packers and Eagles. You can combine these bets into a four-leg parlay, which would significantly increase your payout compared to backing each team separately, but if one team were to lose, then your parlay would not come in.

As previously mentioned, there are also same-game parlay bets, which allow you to bet on several outcomes within a single game.

For example, you could combine the money line, over/under and a player prop in a same-game parlay. This bet would have longer odds than if you were to place each bet individually, but the chances of it coming in are lower due to each leg needing to be a winner.

NFL Live Betting

Another popular way of betting on NFL is live betting, also known as in-play betting.

Live betting is very simple – instead of placing a bet before the game has started, live betting allows you to place a wager while a game is happening.

The advantage of live betting is that it allows you to see the direction in which a game is going before placing a bet.

The downside of live betting is that the selection of markets is often not as extensive as pre-game betting, and the odds might not be as good. 

NFL Futures Bets 

Aside from betting on games every weekend, you can also place wagers on bigger outcomes throughout the season. These are known as futures because, in most cases, you’re betting on something that will not happen immediately.

For example, on the Betway sportsbook, you can bet on teams to win their conference, their division, and the Super Bowl. You can bet on whether teams will make the playoffs and how many wins they’ll get in the regular season.

You can also bet on player milestones such as passing yards, rushing yards, number of touchdowns throughout the season, as well as on NFL awards.

Betting on the Super Bowl & NFL Awards

As part of our futures offering at Betway, you can bet on teams to win the Super Bowl before the season has even started, and throughout the season.

You can also bet on NFL awards, including MVP, Offensive and Defensive Rookie of the Year, and Comeback Player of the Year.

NFL Betting Tips

The Betway Insider will provide weekly NFL betting tips throughout the 2022 season.

NFL Betting FAQs

How many games will each team play and how many bye weeks are there in the NFL regular season?

The 2022 season is comprised of 18 weeks of action. Each team will play 17 games and have one bye week over the course of the season.

What does “covering the spread” mean in sports betting?

When betting against the spread, i.e. placing a wager on the points spread market, the team that eventually wins the bet is said to have covered the spread.

For example, the Patriots (+6.5) are playing the Bills (-6.5).

If the Patriots lose by fewer than seven points, they have covered the spread. If the Bills win by seven points or more, they have covered the spread.

Has any NFL team ever lost every game in a season?

Since the NFL was formed in 1920, 12 teams have had winless seasons: Columbus Panhandles (1922), Columbus Tigers (1925), Cincinnati Reds (1934), Detroit Lions (1942), Chicago Cardinals (1943), Card-Pitt (1944), Brooklyn Tigers (1944), Dallas Cowboys (1960), Tampa Bay Buccaneers (1976), Baltimore Colts (1982), Detroit Lions (2008), Cleveland Browns (2017).

What does it mean for an NFL player to be waived?

When an NFL player is waived by their team, their contract is essentially made available for other teams to pick up.

If this happens during the season, teams have 24 hours to claim a player that has been placed on waivers. If several teams claim one player, the rights are assigned via a priority system based on win-loss record.

If a player is not claimed by the end of the waiver period, known as clearing waivers, they become a free agent.


NFL Betting: Futures Odds & Free Expert Picks

NFL Offensive Player of the Year Odds

NFL Defensive Player of the Year Odds

NFL Defensive Rookie of the Year odds

NFL Comeback of the Year Odds

NFL MVP Betting Odds 

NFL Betting ExplainedHow to bet on NFL games