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With Hurricane Ian ripping through Florida, the location of this game is up in the air. Hurricane winds and outrageous levels of rainfall are proving extremely dangerous, and calling Floridians into actions to protect themselves and their families. Many have evacuated the Tampa area, and the Tampa Bay Bucs are no exception. Earlier this week, the Bucs headed down to Miami so as not to disturb their week's training schedule while all parties work out the best possible site to reposition the game before Sunday night.

Wherever the game ends up being played, this is the next chapter between Patrick Mahomes of the new era, and Tom Brady, the greatest of all time. The game marks the first meeting between the two quarterbacks since the 2021 Super Bowl that resulted in Brady winning his seventh Super Bowl ring.

Chiefs vs Buccaneers Odds, Spread, Over/Under, Moneyline – NFL Betting Lines Week 4

Moneyline: Kansas City Chiefs -115, Tampa Bay Buccaneers -105

Spread: KC Chiefs +1 (-115), Buccaneers -1 (-105)

Total: Over/Under 45 points

The Bucs have had a pretty turbulent start to their season. An opening night win against the Dallas Cowboys marked a great start, but the two outings that followed have been far from ideal. Brady’s group of receivers have been decimated by injuries, as well as depth at running back being a major concern.

Running back Giovani Bernard was placed on IR last week with an ankle injury, while wide receiver Chris Godwin is still working his way back from a hamstring injury. Mike Evans missed the Packers game after getting himself suspended for fighting Saints corner Marshon Lattimore (again), Julio Jones has a knee injury, and both Russell Gage and Breshad Perriman have been limited at practice with knee/hamstring issues of their own.

So just about everybody barring Scotty Miller and tight end Cameron Brate has missed time, or is still missing time, which is always going to cause major issues to the consistency of your offense. Russell Gage had to step up and be the guy against the Packers, catching 12 passes for 87 yards and a touchdown, while Cole Beasley made his Bucs debut with three catches, having been signed as reinforcement just last week.

The question is how healthy are they going to be on Sunday to face Kansas City? There’s only so much the Bucs defense can do before the offense needs to step up. Tampa’s defense was able to hold Aaron Rodgers and the Packers to just 14 points, but even that wasn’t enough for Brady and Co. to overcome.

Mike Evans will be back from suspension, but the first injury report from the Bucs camp this week is still showing a lot of potential problems before the weekend's game. Chris Godwin, Julio Jones and Russell Gage were all limited in practice, while Breshad Perriman didn’t participate.

The Chiefs looked like they were rolling through the first two weeks, but hit a stumbling block in Week 3 against the Indianapolis Colts, who’d been disappointing to say the least in their first two games.

Kansas City failed to run the ball at all, with Mahomes being the team's leading rusher with a grand total of 26 yards. Clyde Edwards-Helaire looked lost, with seven carries for a net zero gain, while Jerick McKinnon led all running backs with seven carries for 20 yards.

That doesn’t bode well against a Bucs team that just shut down the Packers ground game in a low scoring affair. The Chiefs could struggle on the ground again on Sunday, which puts more pressure on Mahomes.

That said, Mahomes has been in fine form this season so far. He’s quickly proven doubters wrong in the aftermath of the Tyreek Hill trade, with many believing the offense would lose a step with one of its best weapons now in Miami. That hasn’t been the case. Mahomes is averaging 285 yards a game, and has thrown eight touchdowns in the first three outings of the year. He’s spreading the football around, with Juju Smith-Schuster emerging as the primary target amongst a new batch of wideouts.

Chiefs vs Buccaneers Prediction & Picks

I feel really good about the Chiefs in this game. For starters, the Bucs have been uprooted from their home facilities, which might not be much of a factor, but could impact a team that is already struggling to find its rhythm so far this season. The danger is always Tom Brady, who will turn it around out of nowhere, and we know better by now than to write him off.

I do like Kansas City, though. They have a full arsenal of weapons, which Mahomes has settled with quickly, despite inconsistencies in the run game. If they can put 24 points on the board, which they’re more than capable of doing in any given game, then I’m not sure the Bucs in their current form can match it.

The Pick: Chiefs Moneyline (-115)

The Over/Under feels high, too. I believe there to be a much stronger possibility of a low-scoring game with the Bucs managing to slow down Mahomes, than there is of a high-scoring game with Brady suddenly orchestrating 30 points out of a patchwork offense.

Over 45 points is going to require both teams hitting 20+, or one team exceeding 30 points. If that’s going to happen, in my mind it will be the Chiefs, as I don’t believe Tampa Bay to be capable of it right now. So I feel good about betting the Chiefs moneyline and the under for the game. If they do then score a lot of points I’m covered, but a low-scoring affair with the winning team hitting around the 21-24 point mark seems about right to me.

The Pick: Under 45 Points (-110)