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Wednesday night offers one of the most exciting moments in the Champions League quarterfinals, with Chelsea traveling to Santiago Bernabeu Stadium for the first fixture in a highly anticipated rivalry matchup with Real Madrid.

We'll provide you with our very own same-game parlay picks and the two best Champions League prop bets for today. So, if you're looking to get ahead in your soccer betting this week, stay tuned for my SGP picks for Real Madrid vs. Chelsea in the Champions League quarterfinals Leg 1.

Real Madrid vs Chelsea Odds & Spread – Champions League Betting Lines 4/12 3-way handicap: Real Madrid -1 (+180) | Draw +1 (+260)  | Chelsea +1 (+115)
Draw No Bet: Real Madrid (-400) | Chelsea (+260)
Over/Under Goals: Over 2.5 (-105) | Under 2.5 (-120)
Double Chance:  Real Madrid or Tie (-600) | Tie or Chelsea (+115) | Real Madrid or Chelsea (-350)
Both teams to score: Yes (-110), No (-118)
1st Goal: Real Madrid (-200) | No Goal (+900) | Chelsea (+200)

Real Madrid vs Chelsea Preview - Champions League Quarter Finals Leg-1

Date: Wednesday, April 12
Time: 3 p.m. EST
TV channel: Paramount+/TUDN
Live stream: Paramount+ 

Although Frank Lampard took over Chelsea’s head-coaching role during a challenging period, his match against his former coach, Carlo Ancelotti, and reigning Champions League winners Real Madrid at the Estadio Santiago Bernabéu might be his most demanding test yet.

Los Blancos will approach this quarterfinal with confidence, as it is a repeat of last season's fixture. However, this time they will initiate the first leg in Madrid instead of traveling to Stamford Bridge. Real Madrid comes off a 3-2 loss to Villarreal on Saturday, while Chelsea have failed to win in four games.

Real Madrid vs Chelsea Lineups & Injuries

Real Madrid has just one injury concern ahead of the match with Ferland Mendy remaining sidelined. This could mean that Eduardo Camavinga will play left-back again, but David Alaba could step in if needed. Thibaut Courtois and Antonio Rudiger will both play against their former Chelsea club, and Rudiger is facing them for the first time.

Chelsea has struggled with injuries this season, which forced Graham Potter to utilize 32 players during his seven-month tenure as manager. However, Frank Lampard received a boost ahead of this crucial Champions League quarterfinal Leg 1 match against Real Madrid, because Thiago Silva, a key player who has already played 27 times in all competitions this season, could return after being sidelined with a knee injury since the end of February. Lampard signed Silva on a free transfer from Paris Saint-Germain in 2020.

Meanwhile, Lampard favorite Mason Mount has returned to training and could be available to play, having recovered from a pelvic injury.

Best 2023 UEFA Champions League Quarterfinal Predictions & Same-Game Parlay Picks Today: Real Madrid vs. Chelsea (+140)Win/Draw/Win

Real Madrid vs. Chelsea is the most lopsided fixture of the Champions League quarterfinals, and the reigning champions are favored to progress to the next round.

Los Blancos must overcome an away second leg this time around, which they didn't have to deal with last season. However, Carlo Ancelotti is well aware of the situation and expected to field an attacking lineup in the first leg at the Bernabéu on Wednesday night. Real Madrid will look to score multiple goals and take a substantial lead to London.

Chelsea's recent struggles make Real Madrid the clear favorites to progress. The London side has failed to win any of their seven matches against other “top six” Premier League teams this season, and they only managed to edge past Borussia Dortmund 2-1 in the previous Champions League round. By contrast, Real Madrid is a team that thrives in big games -- as demonstrated by their 4-0 Clásico victory at the Camp Nou stadium last week and their 6-2 aggregate score over Liverpool.

Although the Stamford Bridge crowd may give Chelsea a boost in the second leg, Real Madrid is more than capable of securing a sizable lead in the first leg. So, for the first match, Los Blancos are the overwhelming favorites.

SGP Pick Leg-1: Real Madrid to Win (-150)

Anytime Goalscorer

Karim Benzema, the French forward, will lead the front line for Real Madrid in the match against Chelsea. Benzema has scored five goals in his four previous meetings with Chelsea, only failing to score once. His hat trick in the first leg of this round last season was crucial to Real Madrid's progression, and he comes into this rematch with two hat tricks in his last three outings.

Benzema had a quiet evening against Villarreal on Saturday, but he had scored three against Real Valladolid and then repeated another treble against Barcelona in midweek. An intense training regimen during the international break seems to have paid off with immediate results.

Benzema's season average for shots on target is 1.99 per 90 minutes, but that has risen to 2.5 per 90 over the last six matches, which include two against La Liga leaders Barcelona as well as meetings with Liverpool, Villarreal, and Real Betis. With Real Madrid leading the competition for shots so far this season, Chelsea might feel vulnerable -- especially against an old enemy like Benzema. I therefore have him scoring anytime as part of this Champions League same-game parlay.

SGP Pick Leg-2: Benzema Anytime Goalscorer (-120)

Odds subject to change*

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