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The NFL playoffs kick off this weekend with six matchups. Twelve teams start their quest for the Lombardi trophy, while the Kansas City Chiefs and Philadelphia Eagles await their next competitors.

For all the teams involved it’s either win or go home, so the stakes couldn't be any higher. The playoffs have come around fast. The regular season is over, and now each team will need to perform at their very best to avoid an early exit.

A few teams entered the playoffs as the underdog, with Seattle being one of them. They travel to San Francisco after qualifying dramatically on the final weekend of the regular season.

The Miami Dolphins will play against the Buffalo Bills once again, with the crucial question being whether quarterback Tua Tagovailoa will be available to play. The Baltimore Ravens also have concerns about their quarterback and have a road game against the Cincinnati Bengals. The Dallas Cowboys, meanwhile, are considered slight favorites to win against the Tampa Bay Buccaneers, despite having to play on the road at Raymond James Stadium in Tampa.

NFL Super Wild Card Weekend Predictions and Best Bets: Picks, Odds & Schedules

AFC Wild Card Playoff Schedule – Chargers @ Jaguars

2022 NFL Super Wild Card Weekend Game
LA Chargers (10-7, 5-4 Away) vs Jacksonville Jaguars (9-8, 5-3 Home)
Date: Saturday, January 14th, 2022
Time: 8:15 p.m. EST
Venue: TIAA Bank Field - Jacksonville, Florida
TV Channel: NBC
Live Stream: Fubo TV
Live Radio: Sirius XM

The Jacksonville Jaguars defeated the Tennessee Titans on the final day of the regular season, thereby winning the AFC South division and earning the No. 4 seed in the wild card round of the NFL playoffs.

The LA Chargers will now travel from the West Coast to the East Coast to play against the Jaguars on their home field. The game will feature a matchup between two young and talented quarterbacks, Justin Herbert of the Chargers and Trevor Lawrence of the Jaguars, which could become quite the head-to-head battle on Saturday night.

Chargers vs Jaguars Odds, Spread, Moneyline, Over/Under - NFL Wild Card Odds

Moneyline: LA Chargers -120, Jacksonville Jaguars +100
Spread: LA Chargers -1 (-115), Jacksonville Jaguars +1 (-105)
Total: Over/Under 47.5 points

Chargers vs Jaguars Preview

The Jacksonville Jaguars figured it out as the season drew to a close, with a five-game win streak that started and finished against their rival Tennessee Titans.

The Jaguars did a great job of defending against running back Derrick Henry during the recent game, which turned out to be a crucial playoff game for both teams, before the actual playoffs began. Henry had 30 carries as the Titans tried to secure a spot in the postseason without their starting quarterback, Ryan Tannehill. However, the Jaguars defense was able to hold Henry to an average of 3.6 yards per carry, effectively shutting down the biggest offensive threat that the Titans had to offer.

As a result of their five-game winning streak, the Jaguars will now advance to play against the Chargers, however, they will face a different challenge as they will have to contend with Justin Herbert and his team.

In the last three games, Jacksonville have faced Josh Dobbs, Davis Mills, and Zach Wilson/Chris Streveler. The week before, they played Dak Prescott and the Dallas Cowboys, and despite Dak turning the ball over twice, Dallas still scored 34 points with three passing touchdowns.

The Jaguars still won that game, but they may face difficulties in the upcoming game against the Chargers due to their heavy passing attack. This type of offense does not play to Jacksonville's strengths on defense, as they have a strong run defense but a weak passing defense, ranking among the bottom five teams in the league for passing yards allowed per game. Herbert, who finished the regular season second in passing yardage behind Patrick Mahomes and has the third-highest yards per game total, could exploit this weakness of the Jaguars.

On the other hand, Jacksonville's strength lies in their front seven on defense. Specifically players such as Foye Oluokun, who leads the league in tackles with 184, Josh Allen, who is a game changer, and Travon Walker, who is developing into a strong player. These players excel in stopping the run game, but if Herbert is given enough time to throw, the Jaguars secondary could struggle against the chargers passing attack.

Trevor Lawrence has had his best year so far this season under new head coach Doug Pederson and staff. The additions on offense have been superb. Christian Kirk cleared 1,100 receiving yards while both Zay Jones and Evan Engram ended the regular season with career highs in receptions and yardage. The Jags are gaining momentum offensively, but is it enough to counterbalance Justin Herbert and his weapons?

The most significant concern arising from Week 18 for the Chargers was the injury to Mike Williams, who had to be taken off the field on a cart and was reportedly in need of assistance as he was experiencing back pain. Williams had difficulty walking after leaving the game and this has led to criticism towards the head coach Brandon Staley for playing his starters in a game with no significance before the playoffs. Additionally, Joey Bosa, who had just returned from injury, also left the game, and there were concerns that he may have reinjured his groin.

Keenan Allen has been a welcome re-addition to the offense, and his presence has been noticeable since he returned in late November. In the eight games since, Allen has had at least 10 targets on four separate occasions, including three games of 14 targets apiece. The veteran star cleared 100 receiving yards twice in the last three weeks, and the Jags will certainly be game-planning to contain him as best they can.

Chargers vs Jaguars Predictions and Wild Card Series Picks for Saturday

This is a great matchup. Trevor Lawrence was the top pick of the 2021 NFL draft and has been showing his strengths with better coaching and talented teammates around him. Justin Herbert has also established himself as a young star in the league, and the two will face off in what is expected to be a close game between the teams.

Despite this, the Chargers are favored to win, even without talented WR Mike Williams. The Chargers have a higher offensive potential and a more effective pass rush than the Jags, and they will likely come out on top in this game, although it's a close call.

The Pick: LA Chargers -1 (-110)

Both offenses have the potential to score points, and this game may turn into a high-scoring battle between two quarterbacks who are not shy about throwing the ball frequently.

The Jags will likely try to control the game to prevent Justin Herbert from throwing for 350 yards and exposing their secondary. However, there is enough offensive talent in this game for the game total to go over.

The Pick: Over 47.5 Points

NFC Wild Card Playoff Schedule – Seahawks @ 49ers

2022-2023 NFL Super Wild Card Weekend Game
Seattle Seahawks (9-8, 4-4 Away) vs San Francisco 49ers (13-4, 8-1 Home)
Date: Saturday, January 14th, 2022
Time: 4:30 p.m. EST
Venue: Levi’s Stadium — Santa Clara, California
TV Channel: FOX
Live Stream: Fubo TV
Live Radio: Sirius XM

After Seattle beat the Rams in overtime in Week 18, all eyes were on Aaron Rogers and his Packers, who would clinch the final playoff spot with a win over the Detroit Lions on Sunday Night Football. Falling behind 20-16 with six minutes left, they couldn't recover. The Seahawks secured the NFC's final seed as a result.

While Seattle was able to muster a win against the Rams, the 49ers will be a new challenge for them as they were unable to defeat San Francisco in their two regular season matchups. Seattle managed to score only 10 points per game in the two games combined, however, they will have another chance to play against the 49ers in the playoffs when it matters the most.

Seahawks vs 49ers Odds, Spread, Moneyline, Over/Under - Wild Card Weekend Betting Lines

Moneyline: Seattle Seahawks +400, San Francisco 49ers -500
Spread: Seattle Seahawks +10 (-110), San Francisco 49ers -10 (-110)
Total: Over/Under 43 points

Seahawks vs 49ers Preview

The Seattle Seahawks' season has been a success. Whichever way you look at it, trading away your franchise quarterback for a haul and having Geno Smith come in and do the job that he has done as Russell Wilson's replacement is an accomplishment. In my mind, this was a defining season in the legacy of Pete Carroll.

The Seahawks have consistently been able to restructure their team year after year, without relying heavily on the NFL draft and avoiding signing high-profile players through free agency. The team's coach, Pete Carroll, has demonstrated that he can consistently coach at a very high level, yet this year presented new challenges. Despite that, Geno Smith has performed admirably as the team's leader on the field, but ultimately it is coach Carroll's strategic decisions that have been instrumental in the team's success.

While the Seattle Seahawks have had a successful season, they now face a challenge that has proven to be beyond their current abilities so far this season.

The 49ers defense gave the Seahawks very little chance to run the ball or control the game in that area of the field. The Seahawks managed just 36 rushing yards in the first game with a combination of Rashaad Penny and Kenneth Walker carrying the football only 10 times. Then, in the second game, Walker ran just 12 times for 47 total yards.

The Seahawks need to have a successful running game to have a chance of winning against the 49ers. This may be difficult as the 49ers have a strong run defense that has not allowed many rushing yards throughout the season. They allow an average of only 77 rushing yards per game and the 49ers defense will likely focus on neutralizing the impact of Seattle's running back Kenneth Walker in the game on Saturday afternoon.

In their second meeting of the regular season, the lack of success in the ground game led to Geno Smith throwing the football 44 times. Despite this, he was able to achieve 238 yards and a touchdown. The problem for Seattle is San Francisco makes you work hard for those yards. The defense is healthy and hungry to continue leading the Niners on a postseason run.

Both teams' quarterbacks have performed well in different situations this season. Brock Purdy has done an exceptional job in leading the team's offense, which is not solely a result of the system but also his preparation, attention to detail, and ability to avoid mistakes.

The 49ers have been successful with a 6-0 record since inserting the rookie into the lineup in their game against the Miami Dolphins. The team should not be underestimated as a potential contender, despite Purdy's status as a seventh-round draft pick. The team is providing Purdy with the necessary support to succeed while he also contributes to the team's success. The 49ers have a well-rounded team, with a well-coordinated offense and a disciplined and expertly coached defense.

The 49ers have demonstrated that they are a formidable outfit, as they have a defense that is able to prevent opposing offenses from scoring more than 13 points. This is complemented by an offense featuring star players such as Christian McCaffrey, Deebo Samuel, and George Kittle, who all provide such different threats in attack.

Additionally, their opponents have lost a key player, Jordyn Brooks, to an ACL injury. At the time of his injury, Brooks was a top tackler in the league and his absence will impact the team's performance.

Seahawks vs 49ers Predictions & NFL Wild Card Picks

Seattle faces a difficult challenge in this game. They will need to play at an extremely high level to win on the road and advance.

Kenneth Walker will be a crucial player for Seattle and, if he is not able to make an impact, it will limit the production of DK Metcalf and Tyler Lockett. Seattle may still be able to score some points and keep themselves in the game, and if they are close in score they may have a chance to force a turnover and win the game.

However, Seattle's defense may struggle to contain Christian McCaffrey and George Kittle, especially with the return of Deebo Samuel from injury. The 49ers will have enough on the day to win, but punters should be beware of a late score which might cash the spread in Seattle's favor.

The Pick: Seattle Seahawks +10 (-110)

All roads lead to the 'Under' here. On the one hand, we have an extremely stubborn and well-equipped 49ers defense. On the other hand, you have a Seattle team that has only managed 10 points on average during the season. The only way the 'over' is achieved here, is if the Niners put up 27+ points, which seems incredibly unlikely as they really might not need to.

Pete Carroll will have analyzed the game footage of the previous games between these two teams and will have made some excellent adjustments. However, there's only so much Seattle can do here against a more powerful roster.

The Pick: Under 43 Points (-110)