The level of competition in the Men’s Sweet Sixteen bracket at this year's March Madness is intense. In the second round, most of the favored teams secured victories, leaving us with 15 teams seeded #6 or higher in the final 16 of the tournament.

The second lowest seed remaining is the #6 ranked Clemson Tigers. The ACC side took down Baylor in the second round and will now look to upset #2 Arizona on their way to the Elite Eight.

Arizona, who continue to be one of the tournament favorites, are vying for their first appearance in the Elite Eight since 2015, and their first in the Final Four in over 20 years.

Arizona vs Clemson Odds, Spread, Moneyline, Over/Under – March Madness Betting Lines 3/28

Moneyline: Arizona (-300), Clemson (+240)
Spread: Arizona -6.5 (-115), Clemson +6.5 (-115)
Total: Over/Under 152.5 points

Arizona vs Clemson Injury Report

The Arizona Wildcats have no injuries to report.

The Clemson Tigers will be missing a few key players for this matchup. Forward Bas Leyte is sidelined due to a shoulder injury he's been nursing for several weeks. Additionally, guard Alex Hemenway is out with a lower leg injury.

Arizona vs Clemson Preview

This West Regional quarterfinal matchup features one of the more unlikely teams in the region, with the Clemson Tigers upsetting Baylor on their way to the Sweet Sixteen.

Clemson came out firing, playing at an elite level against a tough opposition in the second round. They held Baylor to just 25 points in the first half as the Tigers entered the break with a 10-point lead following a buzzer beating three from Chase Hunter.

Brad Brownell’s team refused to let go of that lead in the second half, putting pressure on Baylor to chase the game throughout. Their solid defense shut down Baylor's ball movement and limited open shots, resulting in a 72-64 victory. It stands as one of the standout upsets of the round.

Chase Hunter led the team in scoring (20) and assists (6), firing his team into a matchup with Arizona in the Sweet Sixteen. The senior guard is having a great tournament so far, averaging 20.5 points and six assists a game.

Arizona is looking to get back to their best after losing in the Pac-12 Tournament against Oregon. They strolled past Long Beach State in the opening round of March Madness, before facing Dayton in the second round. The Flyers fought back in the second half, almost closing the gap on the Wildcats following a half time lead.

Eventually, it was Arizona’s talent that pulled through, who extended their lead to double digits and held on to reach the Sweet Sixteen.

One of the key factors here, and something to watch against Clemson, is the amount of point scorers this Wildcats team possesses. The win over Dayton featured 23 bench points, with guard Jaden Bradley scoring 12 points in 27 minutes while rotating in for Kylan Boswell.

Arizona only featured an eight-man rotation, but that was the second straight game now that Bradley contributed off the bench. The former Alabama transfer is in his first season with the Wildcats, averaging 6.7 points and a 46% three-point percentage when coming off the bench.

The Wildcats' effective scoring could prove a problem for Clemson, who have averaged a whole 10 points less than Arizona so far this season. Arizona has great scorers both from three-point range and driving inside, led by ball handling guard Caleb Love.

Clemson’s approach is a little different, with senior center PJ Hall leading the team in scoring with 18.5 points per game. His matchup with Oumar Ballo will be one to keep an eye on in the Sweet Sixteen.

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Points Total

Arizona’s high-flying offense has relaxed a little in recent weeks, playing smart basketball and slowing the game down at the business end of the season. This is a team that has been capable of producing high score totals like the 103-83 win over Oregon in early March, 105 points against Arizona State and 100 over Cal earlier in the season.

However, in recent weeks the Wildcats have slowed their offense, now averaging 71.4 points per game in their last five. The result is five straight unders being cashed, and I like the look of another one here against a Clemson defense that has certainly shown its strength at several intervals this season.

The Pick: Under 152.5 Points (-120)

Spread Bet

That being said, I still like the Wildcats to pull away and cover the spread here. They allowed Dayton to force themselves back into their second round matchup during the second half. Without those couple of runs, Arizona could have won that game by 20+ points.

This time around I expect to see a better defensive effort against a team that relies more on its interior scoring. This is the sort of game where Oumar Ballo’s prowess around the rim could really shine, while the Wildcats guards help to fire the program into the Elite Eight.

Arizona is 2-1-1 against the spread in their last four but are yet to lose one so far at the tournament.

The Pick: Arizona -7.5 (-110)

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