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Saints +4.5 (-110)

The Cowboys are not healthy. Amari Cooper has yet to pass a conditioning test to return, while fellow receiver Cedrick Wilson is also not practicing. With the Saints giving up the fewest yards per carry in the NFL (3.4), the pressure will be on the weakened passing attack of Dallas. 

On top of that, head coach Mike McCarthy is out, so defensive coordinator Dan Quinn will take charge. We have seen in the past how Quinn struggles to operate as both the head coach and defensive play-caller. As he faces the sharp mind of Sean Payton, who had plenty of success against Quinn during the latter’s time in Atlanta, I would rather back the home team getting points.

Dak Prescott over 24.5 completions (-105)

The Saints have the best run defense in the NFL, which should lead to a pass-heavy approach for Dallas. This doesn’t mean Prescott needs to drop back and pass deep. Rather, he will likely have many quick passes throughout the night that act like extended handoffs to his running backs.

This is an easy way to rack up completions. He has over 24.5 completed passes in three of his past five games, including one game where he fell one completion short. 

Dak Prescott over 0.5 interceptions (-110)

More pass attempts leads to a higher chance of interceptions. Prescott has thrown five picks in his last six games.

The Saints also rank joint- sixth in the NFL in interceptions, forcing 1.2 per game. 

Taysom Hill anytime touchdown (+275)

Hill has been practicing as the starting quarterback this week, so we can assume he starts on Thursday. Given the lack of playmakers at receiver for the Saints, this seems like a logical play.

Hill has started and played at least 50 percent of the snaps in six games. He ran for seven total touchdowns in those games, scoring a rushing touchdown in four of them. Expect to see called runs for Hill in the red zone on Thursday.