Visit Betway’s NFL picks page for picks and predictions throughout the season.
Buffalo Bills (-3.5) at Miami Dolphins -105
The Bills had moments where they looked good in Week 1, but the second half was filled with struggles. They now turn around to face a strong divisional foe that already has one AFC East win under its belt this season.
Last season in Miami, Josh Allen passed for 415 yards and four touchdowns. After starting the season on the wrong foot, we could see a similar type of dominating performance, which makes me like the Bills to cover.
New England Patriots (-5.5) at New York Jets -110
Both teams lost in Week 1, but the Patriots looked significantly better than the Jets. On top of that, the Jets lost star left tackle Mekhi Becton to injury.
Bill Belichick is licking his chops. Not only has he dominated rookie quarterbacks in his career, the Jets’ offensive line is getting worse.
Look for the Patriots to bring the pressure and force rookie Zach Wilson into some mistakes, which the Patriots historically capitalize on.
San Francisco 49ers (-3) at Philadelphia Eagles -105
It’s good that the Eagles are feeling positive about themselves after dominating the Falcons in Week 1. However, the 49ers are a much better team than Atlanta.
The Eagles’ strengths are their offensive and defensive lines. However, the 49ers can match or beat them at the point of attack, leading to the focus being on the other players.
It’s no secret that this Philadelphia secondary can be exposed, and I expect San Francisco to do exactly that.
Los Angeles Rams (-3.5) at Indianapolis Colts -110
The Rams looked great in Week 1, led by their new quarterback Matthew Stafford. The Colts, meanwhile, got embarrassed by Russell Wilson and the Seahawks, so this defensive secondary must figure things out quickly.
While I don’t think that happens, that’s not even their biggest worry. That offensive line was not good, and the Rams’ defensive front is tougher than the one the Colts saw last week.
Carson Wentz will again be under a ton of pressure without much talent to throw to.
Kansas City Chiefs (-3.5) at Baltimore Ravens -110
The Chiefs began this season much like last year. They coasted through three quarters, then turned it on late and won the game.
However, this is a game the Chiefs will get up for. They know the Ravens are true AFC contenders, and Kansas City has also owned the Ravens over the past few years.
They met in Baltimore last season, which resulted in a 14-point Kansas City win. Look for them to come out fast and keep that intensity.