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Jacksonville Jaguars at Tennessee Titans (-8.5)

The Titans are coming off their bye week rested and prepared to bounce back. They suffered back-to-back losses going into their bye, so a matchup with a two-win Jaguars team should be exactly what the doctor ordered.

Due to injuries, this Jacksonville team may actually be worse than the one they beat by 18 earlier in the season. The Titans are 3-1 against the spread in divisional games this season, and their rushing attack should lead them to 4-1 in that stat after Sunday.

New Orleans Saints (-5.5) at New York Jets

The Saints lost last week, with Taysom Hill making his first start of the season at quarterback. He also suffered an injured finger in the game, making a poor passing attack worse.

That may actually be a blessing in disguise for this week. If the Saints keep it on the ground with either Hill or Alvin Kamara running the ball, they should win and cover. The Jets have given up 4.7 yards per carry in road games. This defense is good enough to force a couple of turnovers and put this offense in good spots. All they need to do is not make costly errors.

New York Giants (+10) at Los Angeles Chargers

It may seem odd and risky to back the Giants, but hear me out. The Chargers have a COVID outbreak within their building right now, knocking out key players. While we don’t know who will be inactive for the game yet, Keenan Allen, Mike Williams and Chris Harris are all out currently due to the virus.

Having both top wide receivers out of practice cannot be a good thing for the offense, as the timing with Justin Herbert could be affected, as could the offensive installs. The Chargers are only 2-4 against the spread at home this season anyway, so it could be another close game for this team.

Buffalo Bills at Tampa Bay Buccaneers (-3.5)

Tom Brady may now be playing his home football in Tampa, but he will still take a little extra joy from beating one of his old AFC East rivals. The Bills are really struggling right now. They are proving to be incapable of stopping the run.

What’s worse is they lost top cornerback Tre’Davious White, so they can’t overcommit to the run now either, since the secondary isn’t good enough to play man coverage against good teams. Possibly the most troubling thing for the Bills is the play of Josh Allen. While he isn’t horrible, he has taken a step backwards this season, which they cannot afford. Look for Tampa to be efficient offensively and opportunistic on defense.

Chicago Bears at Green Bay Packers (-12.5)

The oldest NFL rivalry will cap off our NFL Sunday. Unfortunately, this is not shaping up to be as interesting or exciting as past season. The Packers are coming off their bye week and slowly, but surely, getting healthier.

After beating the Bears already once this season, they get to do it on their home turf Sunday, facing a Chicago defense without Khalil Mack. Since 2019, the Packers are 17-7 against the spread at home, which is the best record in the NFL. Look for their rowdy home fans to rattle the Bears’ rookie quarterback a bit in this game.