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Cincinnati Bengals at TENNESSEE TITANS -3.5 (-110)

A week after suffering injuries to their defensive line, the Bengals have learned that Derrick Henry will be back to pound the rock for the Titans. Obviously, this is terrible news for Cincinnati, as Henry can attack their weakness.

The Titans’ pass rush will exploit the weakness of the Bengals’ offense, which is their O-line. If Tennessee can come out and score quickly, they should control the tempo the entire game and cover the spread. 

SAN FRANCISCO 49ERS +6 at Green Bay Packers (-110)

This is the most intriguing game of the weekend. The Packers are the heaviest favorite, but the 49ers can clearly attack Green Bay’s run defense. Due to San Francisco’s talent and versatility on offense, I don’t think the Packers will be able to have consistent success stopping them. On offense, however, Aaron Rodgers should be able to pick apart the 49ers.

This is a game where I think the favorite will win the game but not cover the spread. Look for the 49ers to keep it within a touchdown. 

Los Angeles Rams at TAMPA BAY BUCCANEERS -3 (-105)

This game is tough to project without knowing the health of Buccaneers right tackle Tristan Wirfs. If the Tampa offensive line is unable to keep the pressure off Tom Brady, they will need to use Rob Gronkowski to help block, which takes yet another passing option away from a banged-up offense.

However, the Rams offensive line will struggle in both the run and passing games. The pressure will be on Matthew Stafford to perform at a high level, and his mistakes, combined with the calls the Buccaneers will get at home, should be enough for them to win and cover. 

Buffalo Bills at KANSAS CITY CHIEFS -2.5 (-110)

These AFC powers are both coming off blowout victories during Wild Card weekend. The Bills played a perfect game, but if there’s anything we know about the Bills, it’s that they are not consistent. This week, they hit the road to play in a hostile environment.

There’s no doubt that Buffalo will experience more adversity than last week. They usually win big or crumble under pressure, and since it doesn’t seem like they will dominate Kansas City again this weekend, look for Josh Allen to make one mistake too many in a loss.